SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH
Staff
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James Mubiru Send E-mail

Staff Scientist I | Genetics and SNPRC
Phone: 210-258-9744

Education

Doctoral Degree: Ph.D. Animal Physiology (1997)

The University of Hong Kong
Dissertation:

Growth and development of the pancreas and stomach in neonatal pigs.


Master's Degree: M.Ag. and D.V.M. Veterinary Microbiology and Immunology (1994)

South China University of Agriculture Guangzhou , China
Thesis:

Development of killed vaccine against Streptococcus suis type II and use of an Enzyme-Linked Immunosorbent Assay (ELISA) to measure antibody response.


Postdoctoral Work

Postdoctoral Fellow at University of Texas Health Science Center at San Antonio, Department of Pathology July 2002 – 2006
Research on biomakers of prostate cancer to be used in large scale early screening and for the determination of prostate cancer disease prognosis.


Postdoctoral Fellow at University of Texas Health Science Center at San Antonio, Department of Cellular and Structural Biology May 2000 – June 2002
Studies on transgenic mouse lines which are designed to overexpress both the androgen receptor and Bcl-2 in the prostate and serve as an animal model for prostate cancer.

Research Focus

The long-term goal of my research is to develop a nonhuman primate model for the study of the biology of PSA, and to use that model to investigate the various causes of individual variation in serum PSA levels that are not due to cancer itself.  The known (non-cancer) causes of variation in serum levels of PSA include genetic differences among men, obesity, and possibly diet separate from obesity.

Awards and Honors

  • Award for student with excellent academic record for the years 1989, 1990, 1991 and 1992 by South China University of Agriculture.
  • Postgraduate Scholarship by The University of Hong Kong 1994-1997.
  • Conference Grant by the Committee on Research and Conference Grants of The University of Hong Kong in 1995.
  • Conference Grant by Kadoorie Farm & Botanic Garden in November 1999 to attend the 4th International Federation of Organic Agriculture Movements (IFOAM-Asia) held in Tagaytay city Philippines.

 

Publications

Nonhuman primates as models for studies of prostate specific antigen and prostatic diseases.
Mubiru JN, Hubbard GB, Dick EJ Jr, Furman J, Troyer DA, Rogers J
Prostate 68: 1546-1554, 2008
PMID: 18668524

Spontaneous heart disease in the adult chimpanzee (Pan troglodytes).
Seiler BM, Dick Jr EJ, Guardado-Mendoza R, Vandeberg JL, Williams JT, Mubiru JN, Hubbard GB
Journal of Medical Primatology. Epub ahead of print. 2008
PMID: 18671767

Grants

  • Max and Minnie Tomerlin Voelcker Fund 2008: Effects of diet  and obesity on PSA
  • Southwest Foundation forum grant, 2007-2008. $25,000
  • NIH/NCRR 2006: Research Supplement to promote Diversity in Health-related Research.